Summary of analytical results for hydrologic studies of wells open through large intervals of the Snake River plain aquifer at the Idaho National Engineering Laboratory, project 1

This report summarizes results of groundwater analyses for samples collected from wells USGS-44, -45, -46 and -59 in conjunction with the INEL Oversight Program straddle-packer project between 1992 and 1995. The purpose of this project was to develop and deploy a high-quality straddle-packer system for characterization of the three-dimensional geometry of solute plumes and aquifer hydrology near the Idaho Chemical Processing Plant (ICPP). Principle objectives included (1) characterizing vertical variations in aquifer chemistry; (2) documenting deviations in aquifer chemistry from that monitored by the existing network, and (3) making recommendations for improving monitoring efforts

South Dakota State and County Demographic Profiles

Several of South Dakota’s demographic trends are particularly important for planning. This introduction highlights significant trends that are occurring in South Dakota’s counties

Bacteremia in Lung Transplant Recipients in the Current Era

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/71409/1/j.1600-6143.2006.01565.x.pd

Infusion of donor leukocytes to induce tolerance in organ allograft recipients

To further enhance chimerism, 229 primary allograft recipients have received perioperative intravenous infusion of a single dose of 3 to 6 x 108 unmodified donor bone marrow (BM) cells/kg body weight. In addition, 42 patients have been accrued in a concurrent protocol involving multiple (up to three) sequential perioperative infusions of 2 x 108 BM cells/kg/day from day 0-2 posttransplantation (PTx). Organ recipients (n = 133) for whom BM was not available were monitored as controls. The infusion of BM was safe and except for 50 (18%), all study patients have optimal graft function. Of the control patients, allografts in 30 (23%) have been lost during the course of follow-up. The cumulative risk of acute cellular rejection (ACR) was statistically lower in the study patients compared with that of controls. It is interesting that, 62% of BM-augmented heart recipients were free of ACR (Grade ≥ 3A) in the first 6 months PTx compared to controls. The incidence of obliterative bronchiolitis was also statistically lower in study lung recipients (3.8%) compared with the contemporaneously acquired controls (31%). The levels of donor cell chimerism were at least a log higher in the peripheral blood of majority of the study patients compared with that of controls. The incidence of donor-specific hyporeactivity, as determined by one-way mixed leukocyte reaction, was also higher in those BM-augmented liver, kidney, and lung recipients that could be evaluated compared to controls

Stable isotopes infer the diet and habitat of the enigmatic pygmy right whale (Caperea marginata) off southern Australia

In the Southern Hemisphere, baleen whales generally undertake migrations between productive feeding grounds at high latitudes and breeding grounds at lower latitudes. Pygmy right whales (Caperea marginata) (PRW) are the smallest and most enigmatic baleen whale, that likely forgo long-distance migrations, and instead inhabit temperate and subantarctic waters year-round. Previous research has relied on limited data from sighting and stranding records to infer the habitat use and diet of PRWs, however the absence of long-term and consistent data has left uncertainty surrounding these parameters. We utilized bulk stable isotopes of carbon (δ13C) and nitrogen (δ15N) in baleen from Australian PRWs (n = 14) to infer their diet and habitat use. Stable isotope values from 1980–2019 were then matched to remote sensed data from known upwelling regions (where they likely feed) to examine if their dietary patterns are related to changes in food web dynamics. We found that PRWs remained in mid-latitude waters year-round and showed no evidence of feeding in Antarctic waters. Rather, their isotopic record suggests they remain between coastal waters off southern Australia and the Subtropical Convergence, feeding on krill and copepods. Additionally, there was a weak positive relationship between PRW nitrogen stable isotope values and sea surface temperature (SST) from the eastern Great Australian Bight (GAB) and Bonney Upwelling. This suggests seasonal changes in their diet is possibly correlated to oceanographic changes which drive food-web dynamics in these regions. Unlike larger species of baleen whales that migrate further to highly productive waters in the Southern Ocean to meet their energetic demands, the small PRW, who only reach 6.5m, may sustain both feeding and breeding requirements at mid-latitudes. This is the first study to analyze long-term dietary and movement patterns of the PRW, providing an important contribution to our understanding of the species

Impact of Home Visit Capacity on Genetic Association Studies of Late-Onset Alzheimer\u27s Disease

INTRODUCTION—Findings for genetic correlates of late-onset Alzheimer\u27s disease (LOAD) in studies that rely solely on clinic visits may differ from those with capacity to follow participants unable to attend clinic visits. METHODS—We evaluated previously identified LOAD-risk single nucleotide variants in the prospective Adult Changes in Thought study, comparing hazard ratios (HRs) estimated using the full data set of both in-home and clinic visits (n = 1697) to HRs estimated using only data that were obtained from clinic visits (n = 1308). Models were adjusted for age, sex, principal components to account for ancestry, and additional health indicators. RESULTS—LOAD associations nominally differed for 4 of 21 variants; CR1 and APOE variants were significant after Bonferroni correction. DISCUSSION—Estimates of genetic associations may differ for studies limited to clinic-only designs. Home visit capacity should be explored as a possible source of heterogeneity and potential bias in genetic studies

Net neutrality discourses: comparing advocacy and regulatory arguments in the United States and the United Kingdom

Telecommunications policy issues rarely make news, much less mobilize thousands of people. Yet this has been occurring in the United States around efforts to introduce "Net neutrality" regulation. A similar grassroots mobilization has not developed in the United Kingdom or elsewhere in Europe. We develop a comparative analysis of U.S. and UK Net neutrality debates with an eye toward identifying the arguments for and against regulation, how those arguments differ between the countries, and what the implications of those differences are for the Internet. Drawing on mass media, advocacy, and regulatory discourses, we find that local regulatory precedents as well as cultural factors contribute to both agenda setting and framing of Net neutrality. The differences between national discourses provide a way to understand both the structural differences between regulatory cultures and the substantive differences between policy interpretations, both of which must be reconciled for the Internet to continue to thrive as a global medium

Kontrol Diri Dan Kecemasan Komunikasi Interpersonal Pada Pramuwisata

This study aim to analysis relationship of self-control and anxiety of interpersonal communicationin a tourist guide. Product moment corelation analysis (rxy) yields for 0905, to provethe relationship between self-control and interpersonal communication anxiety in a tourist guide.These results indicate a negative relationship between the variables X (Self Control) and variableY (Interpersonal Communication Anxiety in the guides). Social Learning Theory became atheories used in this study, where most of the individual behavior acquired partly the result oflearning through observation of behavior displayed other individuals whose became the model.Elaboration Likelihood Theory which states that each individual will interpret the message orinformation they receive, in accordance with the information they have and their beliefs aboutsomething related to the message. Self-control on the tour guides in Yogyakarta based on thefive major aspects of self-control, that has a very high level of measurement. Includes the abilityto anticipate events, the ability to interpret events and the ability to take decisions. Meanwhile,two other aspects of self control shows the results of measurements at very low category, whichconsists of aspects of behavior and stimulus control. While anxiety based on the three aspects ofinterpersonal communication, which consists of inhibition of the ability to express themselves,lack of interest in communicating and social interaction is interrupted, it indicates the levelmeasurement at very low category. Thus, interpersonal communication anxiety on tour guidesin Yogyakarta can be said to be very low

Net neutrality discourses: comparing advocacy and regulatory arguments in the United States and the United Kingdom

Telecommunications policy issues rarely make news, much less mobilize thousands of people. Yet this has been occurring in the United States around efforts to introduce "Net neutrality" regulation. A similar grassroots mobilization has not developed in the United Kingdom or elsewhere in Europe. We develop a comparative analysis of U.S. and UK Net neutrality debates with an eye toward identifying the arguments for and against regulation, how those arguments differ between the countries, and what the implications of those differences are for the Internet. Drawing on mass media, advocacy, and regulatory discourses, we find that local regulatory precedents as well as cultural factors contribute to both agenda setting and framing of Net neutrality. The differences between national discourses provide a way to understand both the structural differences between regulatory cultures and the substantive differences between policy interpretations, both of which must be reconciled for the Internet to continue to thrive as a global medium

Pretransplant gastroesophageal reflux compromises early outcomes after lung transplantation

ObjectivesGastroesophageal reflux disease (GERD) is implicated as a risk factor for bronchiolitis obliterans syndrome after lung transplantation, but its effects on acute rejection, early allograft function, and survival are unclear. Therefore, we sought to systematically understand the time-related impact of pretransplant GERD on graft function (spirometry), mortality, and acute rejection early after lung transplantation.MethodsFrom January 2005 to July 2008, 215 patients underwent lung transplantation; 114 had preoperative pH testing, and 32 (28%) had objective evidence of GERD. Lung function was assessed by forced 1-second expiratory volume (FEV1; percent of predicted) in 97 patients, mortality by follow-up (median, 2.2 years), and acute rejection by transbronchial biopsy.ResultsPretransplant GERD was associated with decreased FEV1 early after lung transplantation (P = .01) such that by 18 months, FEV1 was 70% of predicted in double lung transplant patients with GERD versus 83% among non-GERD patients (P = .05). A similar decrease was observed in single lung transplantation (50% vs 60%, respectively; P = .09). GERD patients had lower survival early after transplant ( P = .02)—75% versus 90%. Presence of GERD did not affect acute rejection (P = .6).ConclusionsFor lung transplant recipients, pretransplant GERD is associated with worse early allograft function and survival, but not increased acute rejection. The compromise in lung function is substantial, such that FEV1 after double lung transplant in GERD patients approaches that of single lung transplant in non-GERD patients. We advocate thorough testing for GERD before lung transplantation; if identified, aggressive therapy early after transplant, including fundoplication, may prove efficacious